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Chemical structure of BMS-906024

GC35535

BMS-906024

Also known as (2S,3R)-N'-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl)butanediamide

BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor· BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1·6 nM, 0·7 nM, 3·4 nM, and 2·9 nM for Notch1, -2, -3, and -4 receptors, respectively· BMS-906024 demonstrates broad-spectrum antineoplastic activity

ChemicalCAS1401066-79-2MW556.5FormulaC26H26F6N4O3
CAS number
1401066-79-2
Molecular weight
556.5
Formula
C26H26F6N4O3
Solubility
Soluble in DMSO
InChIKey
AYOUDDAETNMCBW-GSHUGGBRSA-N
Catalogue number
GC35535
Brand
GLPBIO
Computed properties PubChem CID 66550890 · XLogP 4.5 · TPSA 105 Ų · H-bond donors 2
XLogP
4.5
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
39

SMILES CN1C2=CC=CC=C2C(=N[C@@H](C1=O)NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(=O)N)C3=CC=CC=C3

Computed descriptors from PubChem (CID 66550890), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.