GC35287
ALK inhibitor 1
Also known as 2-[[5-bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide
ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor· ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM)
ChemicalCAS761436-81-1MW562.48FormulaC23H28BrN7O3S
- CAS number
- 761436-81-1
- Molecular weight
- 562.48
- Formula
- C23H28BrN7O3S
- Solubility
- DMSO： ≥ 100 mg/mL (177·78 mM); Water： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- FTSDLONCFCQDGA-UHFFFAOYSA-N
- Catalogue number
- GC35287
- Brand
- GLPBIO
Computed properties PubChem CID 24857689 · XLogP 4.1 · TPSA 120 Ų · H-bond donors 3
- XLogP
- 4.1
- TPSA
- 120 Ų
- H-bond donors
- 3
- H-bond acceptors
- 10
- Rotatable bonds
- 8
- Heavy atoms
- 35
SMILES CNS(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Br)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
Computed descriptors from PubChem (CID 24857689), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il