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Chemical structure of A-674563 hydrochloride

GC35212

A-674563 hydrochloride

Also known as (2S)-1-[[5-(3-methyl-2H-indazol-5-yl)-3-pyridinyl]oxy]-3-phenylpropan-2-amine;hydrochloride

A-674563 hydrochloride is a potent and selective Akt1 inhibitor with Ki of 11 nM

ChemicalCAS2070009-66-2MW394.9FormulaC22H23ClN4O
CAS number
2070009-66-2
Molecular weight
394.9
Formula
C22H23ClN4O
Solubility
H2O:100 mg/mL (253·23 mM; Need ultrasonic); DMSO:62·5 mg/mL (158·27 mM; Need ultrasonic)
InChIKey
HLNHYVLLEFHBJD-FYZYNONXSA-N
Catalogue number
GC35212
Brand
GLPBIO
Computed properties PubChem CID 73357690 · TPSA 76.8 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
76.8 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
28

SMILES CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OC[C@H](CC4=CC=CC=C4)N.Cl

Computed descriptors from PubChem (CID 73357690), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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