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Chemical structure of 7-Ethylcamptothecin

GC35190

7-Ethylcamptothecin

Also known as (19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

7-Ethylcamptothecin is one of camptothecin analogues· camptothecin (CPT), a cytotoxic alkaloid isolated from Camptotheca acuminate, is shown to have strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models

ChemicalCAS78287-27-1MW376.41FormulaC22H20N2O4
CAS number
78287-27-1
Molecular weight
376.41
Formula
C22H20N2O4
Solubility
DMSO: 5 mg/mL (13·28 mM)
InChIKey
MYQKIWCVEPUPIL-QFIPXVFZSA-N
Catalogue number
GC35190
Brand
GLPBIO
Computed properties PubChem CID 127584 · XLogP 1.8 · TPSA 79.7 Ų · H-bond donors 1
XLogP
1.8
TPSA
79.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
28

SMILES CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC=CC=C51

Computed descriptors from PubChem (CID 127584), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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