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Chemical structure of (S)-Ceralasertib

GC34999

(S)-Ceralasertib

Also known as imino-methyl-[1-[6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]cyclopropyl]-oxo-lambda6-sulfane

(S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2·578 nM·(S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics·(S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition

ChemicalCAS1352226-87-9MW412.51FormulaC20H24N6O2S
CAS number
1352226-87-9
Molecular weight
412.51
Formula
C20H24N6O2S
Solubility
Soluble in DMSO
InChIKey
OHUHVTCQTUDPIJ-MUWSIPGASA-N
Catalogue number
GC34999
Brand
GLPBIO
Computed properties PubChem CID 54761305 · XLogP 2.6 · TPSA 116 Ų · H-bond donors 2
XLogP
2.6
TPSA
116 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
29

SMILES C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)[S@@](=N)(=O)C)C4=C5C=CNC5=NC=C4

Computed descriptors from PubChem (CID 54761305), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.