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Chemical structure of (R)-ADX-47273

GC34985

(R)-ADX-47273

Also known as (4-fluorophenyl)-[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl]methanone

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation

ChemicalCAS851881-59-9MW369.36FormulaC20H17F2N3O2
CAS number
851881-59-9
Molecular weight
369.36
Formula
C20H17F2N3O2
Solubility
DMSO : 100 mg/mL (270·74 mM; Need ultrasonic)
InChIKey
VXQCCZHCFBHTTD-OAHLLOKOSA-N
Catalogue number
GC34985
Brand
GLPBIO
Computed properties PubChem CID 11303165 · XLogP 3.7 · TPSA 59.2 Ų · H-bond donors 0
XLogP
3.7
TPSA
59.2 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
27

SMILES C1C[C@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F

Computed descriptors from PubChem (CID 11303165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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