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Chemical structure of Protosappanin A

GC34742

Protosappanin A

Also known as 5,14,15-trihydroxy-8-oxatricyclo[10.4.0.02,7]hexadeca-1(16),2(7),3,5,12,14-hexaen-10-one

Protosappanin A (PTA), an immunosuppressive ingredient and major biphenyl compound isolated from Caesalpinia sappan L, suppresses JAK2/STAT3-dependent inflammation pathway through down-regulating the phosphorylation of JAK2 and STAT3

ChemicalCAS102036-28-2MW272.25FormulaC15H12O5
CAS number
102036-28-2
Molecular weight
272.25
Formula
C15H12O5
Solubility
DMSO : 125 mg/mL (459·14 mM; Need ultrasonic)
InChIKey
MUKYVRVYBBYJSI-UHFFFAOYSA-N
Catalogue number
GC34742
Brand
GLPBIO
Computed properties PubChem CID 128001 · XLogP 2 · TPSA 87 Ų · H-bond donors 3
XLogP
2
TPSA
87 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
0
Heavy atoms
20

SMILES C1C(=O)COC2=C(C=CC(=C2)O)C3=CC(=C(C=C31)O)O

Computed descriptors from PubChem (CID 128001), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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