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Chemical structure of N-Ethylmaleimide

GC34682

N-Ethylmaleimide

Also known as 1-ethylpyrrole-2,5-dione

N-Ethylmaleimide (NEM) is derived from maleic acid and can alkylate free sulfhydryl groups· It is a protein sulfhydryl modifier that can be used to modify cysteine residues in proteins and peptides· N-Ethylmaleimid inhibits prolyl endopeptidase with an IC50 value of 6·3 μM

ChemicalCAS128-53-0MW125.13FormulaC6H7NO2
CAS number
128-53-0
Molecular weight
125.13
Formula
C6H7NO2
Solubility
DMSO : 50 mg/mL (399·58 mM) Water : 50 mg/mL (399·58 mM), Ethanol : 12·5 mg/mL (99·90 mM)
InChIKey
HDFGOPSGAURCEO-UHFFFAOYSA-N
Catalogue number
GC34682
Brand
GLPBIO
Computed properties PubChem CID 4362 · XLogP 0.9 · TPSA 37.4 Ų · H-bond donors 0
XLogP
0.9
TPSA
37.4 Ų
H-bond donors
0
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
9

SMILES CCN1C(=O)C=CC1=O

Computed descriptors from PubChem (CID 4362), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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