Loading...
Chemical structure of C25-140

GC34513

C25-140

Also known as 1-(4-benzylpiperidin-1-yl)-3-[3,5-dimethyl-1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)pyrazol-4-yl]propan-1-one

C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13

ChemicalCAS1358099-18-9MW457.57FormulaC26H31N7O
CAS number
1358099-18-9
Molecular weight
457.57
Formula
C26H31N7O
Solubility
DMSO ： ≥ 130 mg/mL (284·11 mM)
InChIKey
HFKVRXVHZGBRKF-UHFFFAOYSA-N
Catalogue number
GC34513
Brand
GLPBIO
Computed properties PubChem CID 53093165 · XLogP 3.6 · TPSA 81.2 Ų · H-bond donors 0
XLogP
3.6
TPSA
81.2 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
34

SMILES CC1=C(C(=NN1C2=NN3C(=NN=C3C=C2)C)C)CCC(=O)N4CCC(CC4)CC5=CC=CC=C5

Computed descriptors from PubChem (CID 53093165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.