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Chemical structure of BT-13

GC34509

BT-13

Also known as N,N-diethyl-3-[4-[4-fluoro-2-(trifluoromethyl)benzoyl]piperazin-1-yl]-4-methoxybenzenesulfonamide

BT-13 is a potent and selective glial cell line-derived neurotrophic factor (GDNF) receptor RET agonist independently of GFLs, promoting neurite growth from sensory neurons in vitro and attenuates experimental neuropathy in the Rat

ChemicalCAS924537-98-4MW517.54FormulaC23H27F4N3O4S
CAS number
924537-98-4
Molecular weight
517.54
Formula
C23H27F4N3O4S
Solubility
DMSO: 25 mg/mL (48·31 mM)
InChIKey
GTDJOGZANHPKMR-UHFFFAOYSA-N
Catalogue number
GC34509
Brand
GLPBIO
Computed properties PubChem CID 46088379 · XLogP 3.8 · TPSA 78.5 Ų · H-bond donors 0
XLogP
3.8
TPSA
78.5 Ų
H-bond donors
0
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
35

SMILES CCN(CC)S(=O)(=O)C1=CC(=C(C=C1)OC)N2CCN(CC2)C(=O)C3=C(C=C(C=C3)F)C(F)(F)F

Computed descriptors from PubChem (CID 46088379), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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