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Chemical structure of BIBF0775

GC34493

BIBF0775

Also known as N-ethyl-2-hydroxy-N-methyl-3-[C-phenyl-N-[4-(piperidin-1-ylmethyl)phenyl]carbonimidoyl]-1H-indole-6-carboxamide

BIBF0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor with an IC50 of 34 nM

ChemicalCAS334951-90-5MW494.63FormulaC31H34N4O2
CAS number
334951-90-5
Molecular weight
494.63
Formula
C31H34N4O2
Solubility
DMSO ： 62·5 mg/mL (126·36 mM)
InChIKey
JGQSLTZPBLZNBX-UHFFFAOYSA-N
Catalogue number
GC34493
Brand
GLPBIO
Computed properties PubChem CID 135837779 · XLogP 5.7 · TPSA 71.9 Ų · H-bond donors 2
XLogP
5.7
TPSA
71.9 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
37

SMILES CCN(C)C(=O)C1=CC2=C(C=C1)C(=C(N2)O)C(=NC3=CC=C(C=C3)CN4CCCCC4)C5=CC=CC=C5

Computed descriptors from PubChem (CID 135837779), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.