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Chemical structure of (R)-BAY1238097

GC34443

(R)-BAY1238097

Also known as (4R)-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methylpiperazin-1-yl)phenyl]-4,5-dihydro-2,3-benzodiazepine-3-carboxamide

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097· BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome

ChemicalCAS1564269-85-7MW451.56FormulaC25H33N5O3
CAS number
1564269-85-7
Molecular weight
451.56
Formula
C25H33N5O3
Solubility
DMSO ： 150 mg/mL (332·18 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
CJIPEACKIJJYED-QGZVFWFLSA-N
Catalogue number
GC34443
Brand
GLPBIO
Computed properties PubChem CID 90041345 · XLogP 2.4 · TPSA 69.6 Ų · H-bond donors 1
XLogP
2.4
TPSA
69.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
33

SMILES C[C@@H]1CC2=CC(=C(C=C2C(=NN1C(=O)NC)C3=CC=C(C=C3)N4CCN(CC4)C)OC)OC

Computed descriptors from PubChem (CID 90041345), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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