GC34315
ULK-101
Also known as N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-[6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide
ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1·6 nM and 30 nM for ULK1 and ULK2, respectively· ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress
ChemicalCAS2443816-45-1MW460.45FormulaC22H16F4N4OS
- CAS number
- 2443816-45-1
- Molecular weight
- 460.45
- Formula
- C22H16F4N4OS
- Solubility
- DMSO ： 83·33 mg/mL (180·98 mM);Water ： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- PFZRXJIYAFANHP-IBGZPJMESA-N
- Catalogue number
- GC34315
- Brand
- GLPBIO
Computed properties PubChem CID 137628686 · XLogP 4.9 · TPSA 87.5 Ų · H-bond donors 1
- XLogP
- 4.9
- TPSA
- 87.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 32
SMILES C1CC1[C@@H](C(F)(F)F)NC(=O)C2=CC(=CS2)C3=C4N=CC(=CN4N=C3)C5=CC=C(C=C5)F
Computed descriptors from PubChem (CID 137628686), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il