
GC34195
K-756
Also known as 3-[[1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl]methyl]-1,4-dihydroquinazolin-2-one
K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC50s of 31 and 36 nM, respectively
ChemicalCAS130017-40-2MW433.5FormulaC24H27N5O3
- CAS number
- 130017-40-2
- Molecular weight
- 433.5
- Formula
- C24H27N5O3
- Solubility
- Soluble in DMSO
- InChIKey
- GWXCGEJJQFHPPA-UHFFFAOYSA-N
- Catalogue number
- GC34195
- Brand
- GLPBIO
Computed properties PubChem CID 14668434 · XLogP 3.1 · TPSA 79.8 Ų · H-bond donors 1
- XLogP
- 3.1
- TPSA
- 79.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 32
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)N3CCC(CC3)CN4CC5=CC=CC=C5NC4=O)OC
Computed descriptors from PubChem (CID 14668434), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il