Loading...
Chemical structure of (rel)-MC180295

GC34124

(rel)-MC180295

Also known as [4-amino-2-[[(1S,2S,4R)-2-bicyclo[2.2.1]heptanyl]amino]-1,3-thiazol-5-yl]-(2-nitrophenyl)methanone

(rel)-MC180295 ((rel)-(rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs· (rel)-MC180295 also inhibits GSK-3α and GSK-3β· (rel)-MC180295 ((rel)-(rel)-MC180295) has potent anti-tumor effect

ChemicalCAS2237942-08-2MW358.41FormulaC17H18N4O3S
CAS number
2237942-08-2
Molecular weight
358.41
Formula
C17H18N4O3S
Solubility
DMSO ： 100 mg/mL (279·01 mM)
InChIKey
JRNXAQINDCOHGS-SCVCMEIPSA-N
Catalogue number
GC34124
Brand
GLPBIO
Computed properties PubChem CID 137333456 · XLogP 4.7 · TPSA 142 Ų · H-bond donors 2
XLogP
4.7
TPSA
142 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
25

SMILES C1C[C@H]2C[C@@H]1C[C@@H]2NC3=NC(=C(S3)C(=O)C4=CC=CC=C4[N+](=O)[O-])N

Computed descriptors from PubChem (CID 137333456), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.