Loading...
Chemical structure of Tirabrutinib hydrochloride

GC34097

Tirabrutinib hydrochloride

Also listed as Tirabrutinib hydrochloride (ONO-4059 (hydrochloride))

Tirabrutinib (ONO-4059) hydrochloride is an orally active Bruton's Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6·8 nM

ChemicalCAS1439901-97-9MW490.94FormulaC25H23ClN6O3
CAS number
1439901-97-9
Molecular weight
490.94
Formula
C25H23ClN6O3
Solubility
DMSO： 17·86 mg/mL (36·38 mM)
InChIKey
UQYDCIJFACDXSG-GMUIIQOCSA-N
Catalogue number
GC34097
Brand
GLPBIO
Computed properties PubChem CID 71571562 · TPSA 105 Ų · H-bond donors 2 · H-bond acceptors 6
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
35

SMILES CC#CC(=O)N1CC[C@H](C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N.Cl

Computed descriptors from PubChem (CID 71571562), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.