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Chemical structure of Pamiparib

GC34071

Pamiparib

Also listed as Pamiparib (BGB-290)

Pamiparib (BGB-290) (BGB-290) is an orally active, potent, highly selective PARP inhibitor, with IC50 values of 0·9 nM and 0·5 nM for PARP1 and PARP2, respectively· Pamiparib (BGB-290) has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers including the solid tumor

ChemicalCAS1446261-44-4MW298.31FormulaC16H15FN4O
CAS number
1446261-44-4
Molecular weight
298.31
Formula
C16H15FN4O
Solubility
DMSO ： 83·3 mg/mL (279·24 mM)
InChIKey
DENYZIUJOTUUNY-MRXNPFEDSA-N
Catalogue number
GC34071
Brand
GLPBIO
Computed properties PubChem CID 135565554 · XLogP 1.6 · TPSA 60.5 Ų · H-bond donors 2
XLogP
1.6
TPSA
60.5 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
0
Heavy atoms
22

SMILES C[C@]12CCCN1CC3=NNC(=O)C4=C5C3=C2NC5=CC(=C4)F

Computed descriptors from PubChem (CID 135565554), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.