Loading...
Chemical structure of Trimetrexate

GC33915

Trimetrexate

Also listed as Trimetrexate (CI-898)

Trimetrexate (CI-898) (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4·74 nM and 1·35 nM for human DHFR and Toxoplasma gondii DHFR

ChemicalCAS52128-35-5MW369.42FormulaC19H23N5O3
CAS number
52128-35-5
Molecular weight
369.42
Formula
C19H23N5O3
Solubility
DMSO ： ≥ 61·5 mg/mL (166·48 mM)
InChIKey
NOYPYLRCIDNJJB-UHFFFAOYSA-N
Catalogue number
GC33915
Brand
GLPBIO
Computed properties PubChem CID 5583 · XLogP 2.5 · TPSA 118 Ų · H-bond donors 3
XLogP
2.5
TPSA
118 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
27

SMILES CC1=C(C=CC2=C1C(=NC(=N2)N)N)CNC3=CC(=C(C(=C3)OC)OC)OC

Computed descriptors from PubChem (CID 5583), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.