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Chemical structure of L-Eflornithine (L-DFMO)

GC33414

L-Eflornithine (L-DFMO)

Also known as (2R)-2,5-diamino-2-(difluoromethyl)pentanoic acid

L-Eflornithine (L-DFMO) (L-DFMO) is an enantiomer of Eflornithine· L-Eflornithine (L-DFMO) is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1·3±0·3 μM, and a Kinact of 0·15±0·03 min-1

ChemicalCAS66640-93-5MW182.17FormulaC6H12F2N2O2
CAS number
66640-93-5
Molecular weight
182.17
Formula
C6H12F2N2O2
Solubility
Soluble in DMSO
InChIKey
VLCYCQAOQCDTCN-LURJTMIESA-N
Catalogue number
GC33414
Brand
GLPBIO
Computed properties PubChem CID 6603806 · XLogP -2.9 · TPSA 89.3 Ų · H-bond donors 3
XLogP
-2.9
TPSA
89.3 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
12

SMILES C(C[C@](C(F)F)(C(=O)O)N)CN

Computed descriptors from PubChem (CID 6603806), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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