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Chemical structure of 42-(2-Tetrazolyl)rapamycin

GC33399

42-(2-Tetrazolyl)rapamycin

Also known as (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R,4S)-3-methoxy-4-(tetrazol-2-yl)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1· Rapamycin is a specific mTOR inhibitor

ChemicalCAS221877-56-1MW966.21FormulaC52H79N5O12
CAS number
221877-56-1
Molecular weight
966.21
Formula
C52H79N5O12
Solubility
DMSO ： ≥ 130 mg/mL (134·55 mM)
InChIKey
IURNHYDSJVLLPN-JUKNQOCSSA-N
Catalogue number
GC33399
Brand
GLPBIO
Computed properties PubChem CID 44405767 · XLogP 6.5 · TPSA 219 Ų · H-bond donors 2
XLogP
6.5
TPSA
219 Ų
H-bond donors
2
H-bond acceptors
15
Rotatable bonds
7
Heavy atoms
69

SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5N=CN=N5)C)/C)O)OC)C)C)/C)OC

Computed descriptors from PubChem (CID 44405767), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.