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Chemical structure of BCR-ABL-IN-1

GC33343

BCR-ABL-IN-1

Also known as 4-[1-(3-aminopropyl)indol-4-yl]-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine

BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6·46, and may be used in the research of chronic myelogenous leukemia

ChemicalCAS188260-50-6MW459.44FormulaC23H21F4N5O
CAS number
188260-50-6
Molecular weight
459.44
Formula
C23H21F4N5O
Solubility
Soluble in DMSO
InChIKey
HNAIZJDQDDXEGC-UHFFFAOYSA-N
Catalogue number
GC33343
Brand
GLPBIO
Computed properties PubChem CID 9847014 · XLogP 4.8 · TPSA 78 Ų · H-bond donors 2
XLogP
4.8
TPSA
78 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
33

SMILES C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=C4C=CN(C4=CC=C3)CCCN

Computed descriptors from PubChem (CID 9847014), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.