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Chemical structure of BRD 4354

GC33331

BRD 4354

Also known as 5-chloro-7-[(4-ethylpiperazin-1-yl)-pyridin-3-ylmethyl]quinolin-8-ol

BRD 4354 is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0·85 and 1·88 μM, respectively

ChemicalCAS315698-07-8MW382.89FormulaC21H23ClN4O
CAS number
315698-07-8
Molecular weight
382.89
Formula
C21H23ClN4O
Solubility
DMSO : 125 mg/mL (326·46 mM)
InChIKey
XAFSFXYJOJWLJD-UHFFFAOYSA-N
Catalogue number
GC33331
Brand
GLPBIO
Computed properties PubChem CID 3516032 · XLogP 3.1 · TPSA 52.5 Ų · H-bond donors 1
XLogP
3.1
TPSA
52.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
27

SMILES CCN1CCN(CC1)C(C2=CN=CC=C2)C3=CC(=C4C=CC=NC4=C3O)Cl

Computed descriptors from PubChem (CID 3516032), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.