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Chemical structure of DC-05

GC33148

DC-05

Also known as 1-carbazol-9-yl-3-[2-(1H-indol-3-yl)ethylamino]propan-2-ol

DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 10·3 μM and 1·09 μM, respectively

ChemicalCAS890643-16-0MW383.49FormulaC25H25N3O
CAS number
890643-16-0
Molecular weight
383.49
Formula
C25H25N3O
Solubility
DMSO ： 100 mg/mL (260·76 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
LJWMTSMUQJNHOC-UHFFFAOYSA-N
Catalogue number
GC33148
Brand
GLPBIO
Computed properties PubChem CID 16451230 · XLogP 4.3 · TPSA 53 Ų · H-bond donors 3
XLogP
4.3
TPSA
53 Ų
H-bond donors
3
H-bond acceptors
2
Rotatable bonds
7
Heavy atoms
29

SMILES C1=CC=C2C(=C1)C(=CN2)CCNCC(CN3C4=CC=CC=C4C5=CC=CC=C53)O

Computed descriptors from PubChem (CID 16451230), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.