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Chemical structure of E3 Ligase Ligand-Linker Conjugates 19

GC33129

E3 Ligase Ligand-Linker Conjugates 19

Also known as N-(4-aminobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide

E3 Ligase Ligand-Linker Conjugates 19 (Cereblon Ligand-Linker Conjugates 6), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs

ChemicalCAS1799711-24-2MW402.4FormulaC19H22N4O6
CAS number
1799711-24-2
Molecular weight
402.4
Formula
C19H22N4O6
Solubility
Soluble in DMSO
InChIKey
CPMVDDVEZUNCJN-UHFFFAOYSA-N
Catalogue number
GC33129
Brand
GLPBIO
Computed properties PubChem CID 121410951 · XLogP -0.8 · TPSA 148 Ų · H-bond donors 3
XLogP
-0.8
TPSA
148 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
29

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCN

Computed descriptors from PubChem (CID 121410951), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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