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Chemical structure of Numidargistat

GC33106

Numidargistat

Also listed as CB-1158 (INCB01158)

CB-1158 (INCB01158) (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively· Immuno-oncology agent

ChemicalCAS2095732-06-0MW287.12FormulaC11H22BN3O5
CAS number
2095732-06-0
Molecular weight
287.12
Formula
C11H22BN3O5
Solubility
Soluble in DMSO
InChIKey
ZZJLMZYUGLJBSO-LAEOZQHASA-N
Catalogue number
GC33106
Brand
GLPBIO
Computed properties PubChem CID 131801114 · TPSA 150 Ų · H-bond donors 5 · H-bond acceptors 7
TPSA
150 Ų
H-bond donors
5
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
20

SMILES B(CCC[C@H]1CN(C[C@]1(C(=O)O)N)C(=O)[C@H](C)N)(O)O

Computed descriptors from PubChem (CID 131801114), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.