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Chemical structure of DL-Buthionine-(S,R)-sulfoximine

GC33098

DL-Buthionine-(S,R)-sulfoximine

Also listed as L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine)

L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine) is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels· The IC50 value of L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine) on melanoma, breast and ovarian tumor specimens are 1·9 μM, 8·6 μM, and 29 μM, respectively

ChemicalCAS83730-53-4MW222.31FormulaC8H18N2O3S
CAS number
83730-53-4
Molecular weight
222.31
Formula
C8H18N2O3S
Solubility
Water : 41·67 mg/mL (187·44 mM)
InChIKey
KJQFBVYMGADDTQ-CVSPRKDYSA-N
Catalogue number
GC33098
Brand
GLPBIO
Computed properties PubChem CID 119565 · XLogP -0.6 · TPSA 113 Ų · H-bond donors 3
XLogP
-0.6
TPSA
113 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
14

SMILES CCCCS(=N)(=O)CC[C@@H](C(=O)O)N

Computed descriptors from PubChem (CID 119565), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.