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Chemical structure of Rociletinib hydrobromide

GC33061

Rociletinib hydrobromide

Also listed as Rociletinib hydrobromide (CO-1686 (hydrobromide))

Rociletinib hydrobromide (CO-1686 (hydrobromide)) (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21·5 nM and 303·3 nM, respectively

ChemicalCAS1446700-26-0MW636.46FormulaC27H29BrF3N7O3
CAS number
1446700-26-0
Molecular weight
636.46
Formula
C27H29BrF3N7O3
Solubility
DMSO : ≥ 59 mg/mL (92·70 mM)
InChIKey
IPKRDUJIGYXXNT-UHFFFAOYSA-N
Catalogue number
GC33061
Brand
GLPBIO
Computed properties PubChem CID 71725151 · TPSA 112 Ų · H-bond donors 4 · H-bond acceptors 11
TPSA
112 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
8
Heavy atoms
41

SMILES CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC.Br

Computed descriptors from PubChem (CID 71725151), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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