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Chemical structure of FN-1501

GC33049

FN-1501

Also known as N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1H-pyrazole-5-carboxamide

FN-1501 is a potent inhibitor of FLT3 and CDK, with IC50s of 2·47, 0·85, 1·96, and 0·28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively· FN-1501 has anticancer activity

ChemicalCAS1429515-59-2MW431.49FormulaC22H25N9O
CAS number
1429515-59-2
Molecular weight
431.49
Formula
C22H25N9O
Solubility
DMSO ： ≥ 50 mg/mL (115·88 mM)
InChIKey
VXLAKHWYGRKCGI-UHFFFAOYSA-N
Catalogue number
GC33049
Brand
GLPBIO
Computed properties PubChem CID 72195175 · XLogP 2.2 · TPSA 118 Ų · H-bond donors 4
XLogP
2.2
TPSA
118 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
32

SMILES CN1CCN(CC1)CC2=CC=C(C=C2)NC(=O)C3=C(C=NN3)NC4=NC=NC5=C4C=CN5

Computed descriptors from PubChem (CID 72195175), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.