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Chemical structure of NSC781406

GC33014

NSC781406

Also known as 2,4-difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]-3-pyridinyl]benzenesulfonamide

A dual inhibitor of PI3K and mTOR

ChemicalCAS1676893-24-5MW627.68FormulaC29H27F2N5O5S2
CAS number
1676893-24-5
Molecular weight
627.68
Formula
C29H27F2N5O5S2
Solubility
DMSO : ≥ 150 mg/mL (238·98 mM)
InChIKey
BBRINJUWZRLWKK-UHFFFAOYSA-N
Catalogue number
GC33014
Brand
GLPBIO
Computed properties PubChem CID 127025628 · XLogP 3.1 · TPSA 139 Ų · H-bond donors 1
XLogP
3.1
TPSA
139 Ų
H-bond donors
1
H-bond acceptors
12
Rotatable bonds
8
Heavy atoms
43

SMILES COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C#CCN4CCN(CC4)S(=O)(=O)C)NS(=O)(=O)C5=C(C=C(C=C5)F)F

Computed descriptors from PubChem (CID 127025628), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.