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Chemical structure of IBR2

GC32912

IBR2

Also known as 2-benzylsulfonyl-1-(1H-indol-3-yl)-1H-isoquinoline

IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair· IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis

ChemicalCAS313526-24-8MW400.49FormulaC24H20N2O2S
CAS number
313526-24-8
Molecular weight
400.49
Formula
C24H20N2O2S
Solubility
DMSO : ≥ 150 mg/mL (374·54 mM)
InChIKey
YCOHEPDJLXZVBZ-UHFFFAOYSA-N
Catalogue number
GC32912
Brand
GLPBIO
Computed properties PubChem CID 4664423 · XLogP 4.5 · TPSA 61.6 Ų · H-bond donors 1
XLogP
4.5
TPSA
61.6 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
29

SMILES C1=CC=C(C=C1)CS(=O)(=O)N2C=CC3=CC=CC=C3C2C4=CNC5=CC=CC=C54

Computed descriptors from PubChem (CID 4664423), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.