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Chemical structure of GNF-6231

GC32877

GNF-6231

Also known as N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-fluoro-4-pyridinyl)-5-methyl-3-pyridinyl]acetamide

GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling

ChemicalCAS1243245-18-2MW448.49FormulaC24H25FN6O2
CAS number
1243245-18-2
Molecular weight
448.49
Formula
C24H25FN6O2
Solubility
DMSO : ≥ 36 mg/mL (80·27 mM)
InChIKey
AXXNRMISICMFNS-UHFFFAOYSA-N
Catalogue number
GC32877
Brand
GLPBIO
Computed properties PubChem CID 46927297 · XLogP 1.7 · TPSA 91.3 Ų · H-bond donors 1
XLogP
1.7
TPSA
91.3 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
33

SMILES CC1=CC(=CN=C1C2=CC(=NC=C2)F)CC(=O)NC3=NC=C(C=C3)N4CCN(CC4)C(=O)C

Computed descriptors from PubChem (CID 46927297), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.