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Chemical structure of AZM475271 (M475271)

GC32875

AZM475271 (M475271)

Also known as N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine

AZM475271 (M475271) is a potent and selective Src kinase inhibitor with IC50 of 5 nM; no inhibitory activity on Flt3, KDR, Tie-2

ChemicalCAS476159-98-5MW442.94FormulaC23H27ClN4O3
CAS number
476159-98-5
Molecular weight
442.94
Formula
C23H27ClN4O3
Solubility
DMSO : ≥ 42 mg/mL (94·82 mM)
InChIKey
WPOXAFXHRJYEIC-UHFFFAOYSA-N
Catalogue number
GC32875
Brand
GLPBIO
Computed properties PubChem CID 5330175 · XLogP 4.7 · TPSA 68.7 Ų · H-bond donors 1
XLogP
4.7
TPSA
68.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
31

SMILES CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=CC(=C4)OC)Cl)OC

Computed descriptors from PubChem (CID 5330175), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.