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Chemical structure of Flumatinib

GC32867

Flumatinib

Also listed as Flumatinib (HHGV678)

Flumatinib (HHGV678) (HHGV678) is an orally available, selective inhibitor of Bcr-Abl· Flumatinib (HHGV678) inhibits c-Abl, PDGFRβ and c-Kit with IC50s of 1·2 nM, 307·6 nM and 665·5 nM, respectively

ChemicalCAS895519-90-1MW562.59FormulaC29H29F3N8O
CAS number
895519-90-1
Molecular weight
562.59
Formula
C29H29F3N8O
Solubility
DMSO : ≥ 32 mg/mL (56·88 mM)
InChIKey
BJCJYEYYYGBROF-UHFFFAOYSA-N
Catalogue number
GC32867
Brand
GLPBIO
Computed properties PubChem CID 46848036 · XLogP 3.4 · TPSA 99.2 Ų · H-bond donors 2
XLogP
3.4
TPSA
99.2 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
41

SMILES CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5

Computed descriptors from PubChem (CID 46848036), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.