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Chemical structure of BMS-986195

GC32844

BMS-986195

Also known as 4-[(3S)-3-(but-2-ynoylamino)piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide

BMS-986195 (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Bruton's tyrosine kinase (BTK), with an IC50 of 0·1 nM

ChemicalCAS1912445-55-6MW370.42FormulaC20H23FN4O2
CAS number
1912445-55-6
Molecular weight
370.42
Formula
C20H23FN4O2
Solubility
DMSO ： ≥ 100 mg/mL (269·96 mM)
InChIKey
VJPPLCNBDLZIFG-ZDUSSCGKSA-N
Catalogue number
GC32844
Brand
GLPBIO
Computed properties PubChem CID 121293929 · XLogP 2.8 · TPSA 91.2 Ų · H-bond donors 3
XLogP
2.8
TPSA
91.2 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
27

SMILES CC#CC(=O)N[C@H]1CCCN(C1)C2=C(C=C(C3=C2C(=C(N3)C)C)C(=O)N)F

Computed descriptors from PubChem (CID 121293929), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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