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Chemical structure of R-268712

GC32840

R-268712

Also known as 2-[4-[2-fluoro-5-[5-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol

R-268712 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2·5 nM

ChemicalCAS879487-87-3MW363.39FormulaC20H18FN5O
CAS number
879487-87-3
Molecular weight
363.39
Formula
C20H18FN5O
Solubility
DMSO ： 125 mg/mL (343·98 mM)
InChIKey
JQGOCCALXFSRHZ-UHFFFAOYSA-N
Catalogue number
GC32840
Brand
GLPBIO
Computed properties PubChem CID 11703284 · XLogP 2.2 · TPSA 79.6 Ų · H-bond donors 2
XLogP
2.2
TPSA
79.6 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
27

SMILES CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO

Computed descriptors from PubChem (CID 11703284), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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