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Chemical structure of Ipatasertib dihydrochloride

GC32794

Ipatasertib dihydrochloride

Also listed as Ipatasertib dihydrochloride (GDC-0068 (dihydrochloride))

Ipatasertib dihydrochloride (GDC-0068 (dihydrochloride)) (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively

ChemicalCAS1396257-94-5MW530.92FormulaC24H34Cl3N5O2
CAS number
1396257-94-5
Molecular weight
530.92
Formula
C24H34Cl3N5O2
Solubility
DMSO : 125 mg/mL (235·44 mM);Water : ≥ 41 mg/mL (77·22 mM)
InChIKey
SRKVNRNRVFDUTG-VISIQVHMSA-N
Catalogue number
GC32794
Brand
GLPBIO
Computed properties PubChem CID 62707512 · TPSA 81.6 Ų · H-bond donors 4 · H-bond acceptors 6
TPSA
81.6 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
34

SMILES C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O.Cl.Cl

Computed descriptors from PubChem (CID 62707512), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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