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Chemical structure of Gamitrinib TPP hexafluorophosphate

GC32766

Gamitrinib TPP hexafluorophosphate

Also known as 6-[[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-9-carbamoyloxy-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-19-yl]amino]hexyl-triphenylphosphanium hexafluorophosphate

Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor· Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity

ChemicalCAS1131626-47-5MW1036.03FormulaC52H65F6N3O8P2
CAS number
1131626-47-5
Molecular weight
1036.03
Formula
C52H65F6N3O8P2
Solubility
DMSO: 50 mg/mL (48·26 mM)
InChIKey
NFIBTCZSRLMDOD-WLXHSWTPSA-O
Catalogue number
GC32766
Brand
GLPBIO
Computed properties PubChem CID 25232581 · TPSA 166 Ų · H-bond donors 4 · H-bond acceptors 16
TPSA
166 Ų
H-bond donors
4
H-bond acceptors
16
Rotatable bonds
15
Heavy atoms
71

SMILES C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)/C)OC)OC(=O)N)\C)C)O)OC.F[P-](F)(F)(F)(F)F

Computed descriptors from PubChem (CID 25232581), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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