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Chemical structure of RA190

GC32765

RA190

Also known as (3Z,5Z)-1-[(2S)-2-amino-3-phenylpropanoyl]-3,5-bis[(3,4-dichlorophenyl)methylidene]piperidin-4-one;hydrochloride

RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13

ChemicalCAS1617495-03-0MW596.76FormulaC28H23Cl5N2O2
CAS number
1617495-03-0
Molecular weight
596.76
Formula
C28H23Cl5N2O2
Solubility
DMSO ： ≥ 100 mg/mL (167·57 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
UMWXLEVUBFNYIK-VCCJZKHWSA-N
Catalogue number
GC32765
Brand
GLPBIO
Computed properties PubChem CID 126843229 · TPSA 63.4 Ų · H-bond donors 2 · H-bond acceptors 3
TPSA
63.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
37

SMILES C\1N(C/C(=C/C2=CC(=C(C=C2)Cl)Cl)/C(=O)/C1=C\C3=CC(=C(C=C3)Cl)Cl)C(=O)[C@@H](N)CC4=CC=CC=C4.Cl

Computed descriptors from PubChem (CID 126843229), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.