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Chemical structure of CA-4948

GC32748

CA-4948

Also known as 6-(6-amino-3-pyridinyl)-N-(2-morpholin-4-yl-[1,3]oxazolo[4,5-b]pyridin-6-yl)pyridine-2-carboxamide

CA-4948 is a selective, potent and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, extracted from patent WO2015104688 (example 1)

ChemicalCAS1801343-74-7MW417.42FormulaC21H19N7O3
CAS number
1801343-74-7
Molecular weight
417.42
Formula
C21H19N7O3
Solubility
DMSO ： 13·89 mg/mL (33·28 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
RWIMETUXCNDSLE-UHFFFAOYSA-N
Catalogue number
GC32748
Brand
GLPBIO
Computed properties PubChem CID 118224238 · XLogP 1.5 · TPSA 132 Ų · H-bond donors 2
XLogP
1.5
TPSA
132 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
4
Heavy atoms
31

SMILES C1COCCN1C2=NC3=C(O2)C=C(C=N3)NC(=O)C4=CC=CC(=N4)C5=CN=C(C=C5)N

Computed descriptors from PubChem (CID 118224238), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.