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Chemical structure of LSKL, Inhibitor of Thrombospondin TSP-1

GC32728

LSKL, Inhibitor of Thrombospondin TSP-1

Also known as (2S)-6-amino-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]hexanamide

LSKL, Inhibitor of Thrombospondin TSP-1 is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist· LSKL, Inhibitor of Thrombospondin TSP-1 inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis· LSKL, Inhibitor of Thrombospondin TSP-1 suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH)· LSKL, Inhibitor of Thrombospondin TSP-1 can readily crosse the blood-brain barrier

ChemicalCAS283609-79-0MW458.6FormulaC21H42N6O5
CAS number
283609-79-0
Molecular weight
458.6
Formula
C21H42N6O5
Solubility
DMSO ： ≥ 100 mg/mL (218·05 mM)
InChIKey
YOKXDNNIFSAXBY-QAETUUGQSA-N
Catalogue number
GC32728
Brand
GLPBIO
Computed properties PubChem CID 71312184 · XLogP -1.2 · TPSA 203 Ų · H-bond donors 7
XLogP
-1.2
TPSA
203 Ų
H-bond donors
7
H-bond acceptors
7
Rotatable bonds
16
Heavy atoms
32

SMILES CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N)N

Computed descriptors from PubChem (CID 71312184), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.