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Chemical structure of Ac-DEVD-CHO

GC32695

Ac-DEVD-CHO

Also known as (4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Ac-DEVD-CHO is a Caspase-3 inhibitor with an IC50 value of 0·016μM

ChemicalCAS169332-60-9MW502.47FormulaC20H30N4O11
CAS number
169332-60-9
Molecular weight
502.47
Formula
C20H30N4O11
Solubility
Water : ≥ 50 mg/mL (99·51 mM)
InChIKey
UMBVAPCONCILTL-MRHIQRDNSA-N
Catalogue number
GC32695
Brand
GLPBIO
Computed properties PubChem CID 644345 · XLogP -2.6 · TPSA 245 Ų · H-bond donors 7
XLogP
-2.6
TPSA
245 Ų
H-bond donors
7
H-bond acceptors
11
Rotatable bonds
16
Heavy atoms
35

SMILES CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)C

Computed descriptors from PubChem (CID 644345), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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