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Chemical structure of Gepotidacin (GSK2140944)

GC32088

Gepotidacin (GSK2140944)

Also known as (3R)-3-[[4-(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.04,12]dodeca-6,8(12),9-triene-5,11-dione

Gepotidacin (GSK2140944) is a novel, bactericidal, oral, triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking two essential topoisomerase enzymes

ChemicalCAS1075236-89-3MW448.52FormulaC24H28N6O3
CAS number
1075236-89-3
Molecular weight
448.52
Formula
C24H28N6O3
Solubility
DMSO : 7·14 mg/mL (15·92 mM)
InChIKey
PZFAZQUREQIODZ-LJQANCHMSA-N
Catalogue number
GC32088
Brand
GLPBIO
Computed properties PubChem CID 25101874 · XLogP 0.1 · TPSA 90.4 Ų · H-bond donors 1
XLogP
0.1
TPSA
90.4 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
33

SMILES C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6

Computed descriptors from PubChem (CID 25101874), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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