Loading...
Chemical structure of PGS-IN-1 (KME-4)

GC32038

PGS-IN-1 (KME-4)

Also known as (3E)-3-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]oxolan-2-one

PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS) with an IC50 of 0·28 μM; also inhibits 5-lipoxygenase with an IC50 of 1·05 μM

ChemicalCAS102271-49-8MW302.41FormulaC19H26O3
CAS number
102271-49-8
Molecular weight
302.41
Formula
C19H26O3
Solubility
Soluble in DMSO
InChIKey
DFPYHQJPGCODSB-UKTHLTGXSA-N
Catalogue number
GC32038
Brand
GLPBIO
Computed properties PubChem CID 6438990 · XLogP 5.2 · TPSA 46.5 Ų · H-bond donors 1
XLogP
5.2
TPSA
46.5 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
22

SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C/2\CCOC2=O

Computed descriptors from PubChem (CID 6438990), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.