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Chemical structure of ZD8321

GC32005

ZD8321

Also known as methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-[[(3S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamate

ZD8321 is a potent inhibitor of human Neutrophil elastase (NE) with a Ki of 13±1·7 nM

ChemicalCAS182073-77-4MW423.43FormulaC18H28F3N3O5
CAS number
182073-77-4
Molecular weight
423.43
Formula
C18H28F3N3O5
Solubility
Soluble in DMSO
InChIKey
ZYLBZJKJNAYAFU-AVGNSLFASA-N
Catalogue number
GC32005
Brand
GLPBIO
Computed properties PubChem CID 9910174 · XLogP 2.9 · TPSA 105 Ų · H-bond donors 2
XLogP
2.9
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
29

SMILES CC(C)[C@@H](C(=O)C(F)(F)F)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)OC

Computed descriptors from PubChem (CID 9910174), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.