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Chemical structure of Chymase-IN-1

GC31930

Chymase-IN-1

Also known as [1-(5-chloro-1-benzothiophen-3-yl)-2-(naphthalen-2-ylamino)-2-oxoethyl]phosphonic acid

Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM

ChemicalCAS862090-74-2MW431.83FormulaC20H15ClNO4PS
CAS number
862090-74-2
Molecular weight
431.83
Formula
C20H15ClNO4PS
Solubility
Soluble in DMSO
InChIKey
HUJXISJLAPAFBO-UHFFFAOYSA-N
Catalogue number
GC31930
Brand
GLPBIO
Computed properties PubChem CID 11235804 · XLogP 4.4 · TPSA 115 Ų · H-bond donors 3
XLogP
4.4
TPSA
115 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
28

SMILES C1=CC=C2C=C(C=CC2=C1)NC(=O)C(C3=CSC4=C3C=C(C=C4)Cl)P(=O)(O)O

Computed descriptors from PubChem (CID 11235804), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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