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Chemical structure of ZK824859

GC31889

ZK824859

Also known as (2R)-2-[[6-[3-[3-(aminomethyl)phenyl]-5-methylphenoxy]-3,5-difluoro-2-pyridinyl]oxy]butanoic acid

ZK824859 is an oral available and selective urokinase plasminogen activator (uPA) inhibitor with IC50s of 79?nM, 1580?nM and 1330?nM for human uPA, tPA, and plasmin, respectively

ChemicalCAS2271122-53-1MW428.43FormulaC23H22F2N2O4
CAS number
2271122-53-1
Molecular weight
428.43
Formula
C23H22F2N2O4
Solubility
Soluble in DMSO
InChIKey
CVNXUNVHFJANHX-HXUWFJFHSA-N
Catalogue number
GC31889
Brand
GLPBIO
Computed properties PubChem CID 69496820 · XLogP 2.3 · TPSA 94.7 Ų · H-bond donors 2
XLogP
2.3
TPSA
94.7 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
31

SMILES CC[C@H](C(=O)O)OC1=C(C=C(C(=N1)OC2=CC(=CC(=C2)C3=CC=CC(=C3)CN)C)F)F

Computed descriptors from PubChem (CID 69496820), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.