GC31846
Complement factor D-IN-1
Also known as 1-[2-[(1R,3S,5R)-3-[(6-bromo-2-pyridinyl)carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxoethyl]indazole-3-carboxamide
Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC50s of 0·006 and 0·05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively
ChemicalCAS1386455-76-0MW483.32FormulaC21H19BrN6O3
- CAS number
- 1386455-76-0
- Molecular weight
- 483.32
- Formula
- C21H19BrN6O3
- Solubility
- DMSO： 250 mg/mL (517·26 mM)
- InChIKey
- CWZUTHDJLNZLCM-DFBGVHRSSA-N
- Catalogue number
- GC31846
- Brand
- GLPBIO
Computed properties PubChem CID 86673884 · XLogP 2.2 · TPSA 123 Ų · H-bond donors 2
- XLogP
- 2.2
- TPSA
- 123 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 31
SMILES C1[C@H]2[C@@H]1N([C@@H](C2)C(=O)NC3=NC(=CC=C3)Br)C(=O)CN4C5=CC=CC=C5C(=N4)C(=O)N
Computed descriptors from PubChem (CID 86673884), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il