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Chemical structure of PRT062607 (P505-15)

GC31819

PRT062607 (P505-15)

Also known as 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide

PRT062607 (P505-15)(P505-15; PRT-2607; BIIB-057) is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM; >80-fold selective for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70

ChemicalCAS1370261-96-3MW393.45FormulaC19H23N9O
CAS number
1370261-96-3
Molecular weight
393.45
Formula
C19H23N9O
Solubility
DMF： 50 mg/ml,DMF：PBS(pH 7·2)(1：1)： 0·5 mg/ml,DMSO： 25 mg/ml,Ethanol： 10 mg/ml
InChIKey
TXGKRVFSSHPBAJ-JKSUJKDBSA-N
Catalogue number
GC31819
Brand
GLPBIO
Computed properties PubChem CID 44462758 · XLogP 2.2 · TPSA 150 Ų · H-bond donors 4
XLogP
2.2
TPSA
150 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
29

SMILES C1CC[C@H]([C@H](C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N

Computed descriptors from PubChem (CID 44462758), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.