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Chemical structure of ReN-1869 hydrochloride

GC31812

ReN-1869 hydrochloride

Also listed as ReN-1869 hydrochloride (NNC-05-1869 hydrochloride)

ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0·19±0·04 μM and the non-selective σ site (guinea pig brain) with Ki of 0·45 μM

ChemicalCAS170149-76-5MW397.94FormulaC24H28ClNO2
CAS number
170149-76-5
Molecular weight
397.94
Formula
C24H28ClNO2
Solubility
Soluble in DMSO
InChIKey
OJCOPCYFLFDPTD-VEIFNGETSA-N
Catalogue number
GC31812
Brand
GLPBIO
Computed properties PubChem CID 9800975 · TPSA 40.5 Ų · H-bond donors 2 · H-bond acceptors 3
TPSA
40.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
28

SMILES C1C[C@H](CN(C1)CCC=C2C3=CC=CC=C3CCC4=CC=CC=C42)C(=O)O.Cl

Computed descriptors from PubChem (CID 9800975), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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