Loading...
Chemical structure of Bz 423 (BZ48)

GC31806

Bz 423 (BZ48)

Also known as 7-chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-3H-1,4-benzodiazepin-2-one

Bz 423 (BZ48) is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak

ChemicalCAS216691-95-1MW440.92FormulaC27H21ClN2O2
CAS number
216691-95-1
Molecular weight
440.92
Formula
C27H21ClN2O2
Solubility
DMSO : ≥ 125 mg/mL (283·50 mM)
InChIKey
HIJCSNHREFFOML-UHFFFAOYSA-N
Catalogue number
GC31806
Brand
GLPBIO
Computed properties PubChem CID 644335 · XLogP 5.6 · TPSA 52.9 Ų · H-bond donors 1
XLogP
5.6
TPSA
52.9 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
32

SMILES CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)CC3=CC4=CC=CC=C4C=C3)C5=CC=C(C=C5)O

Computed descriptors from PubChem (CID 644335), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.